#Whats imy mean how to#
#Whats imy mean trial#

IMY is an acronym that stands for “I Miss You.” It is commonly used in text messages, emails, and social media to express feelings of sadness or nostalgia when the sender thinks about the person being missed. Learn about clinical trials currently looking for people with INAD at. Clinical research uses human volunteers to help researchers learn more about a disorder and perhaps find better ways to safely detect, treat, or prevent disease.Īll types of volunteers are needed- those who are healthy or may have an illness or disease- of all different ages, sexes, races, and ethnicities to ensure that study results apply to as many people as possible, and that treatments will be safe and effective for everyone who will use them.įor information about participating in clinical research visit NIH Clinical Research Trials and You.

#Whats imy mean trial#

How can I or my loved one help improve care for people with infantile neuroaxonal dystrophy?Ĭonsider participating in a clinical trial so clinicians and scientists can learn more about the INAD and related disorders.

#Whats imy mean how to#

Physiotherapists and physical therapists can teach parents and caregivers how to position and seat their child and exercise the child's arms and legs to help him or her stay comfortable. Treatment is symptomatic and may include medications to reduce pain and to sedate (help the child stay calm). There is no cure for INAD and there is no treatment that can stop the disease from getting worse. Tissue biopsy of skin, rectum, nerve or conjunctive tissue may be used to confirm the presence of characteristic swellings (spheroid bodies) in the nerve axons. How is infantile neuroaxonal dystrophy diagnosed and treated?Įlectrophysiology (nerve conduction velocities) may be helpful for diagnosis.

While the basic genetic and metabolic causes are unknown, INAD is the result of an abnormal build-up of toxic substances in nerves that communicate with muscles, skin, and the conjunctive tissue around the eyes. Mutations in the PLA2G6 gene have been identified in most children with INAD. That means that both parents must be carriers of the defective gene that causes INAD to pass it on to their child.

Who is more likely to get infantile neuroaxonal dystrophy? INAD is a progressive disease. In other words, once symptoms begin, they will get worse over time.

Loss of the ability to sit, crawl, or walkĮventually, because of the loss of vision, speech, and mental skills, the child will lose touch with his or her surroundings.Floppiness in the head, body, and legs (more than in the arms).Rapid, wobbly eye movements and squints may be the first symptoms. Symptoms usually start in the first two years of life. Generally, a baby's development starts to slow down between the ages of six months to three years. These could include:įor their first few years, a baby with INAD will be alert and responsive, but will become more physically impaired as time passes. These symptoms get worse as time passes.Ĭertain facial deformities may be present at birth. INAD causes loss of vision, muscular control, and mental skills. It affects axons, the part of a neuron (nerve cell) that carries messages from the brain to other parts of the body. Infantile neuroaxonal dystrophy (INAD) is a rare, inherited disorder of the body's nervous system. What is infantile neuroaxonal dystrophy (INAD)?